The genetic underpinnings of body fat distribution

Sexual dimorphisms in genetic loci linked to body fat distribution

Obesity is a chronic condition associated with increased morbidity and mortality and is a risk factor for a number of other diseases including type 2 diabetes and cardiovascular disease. Obesity confers an enormous, costly burden on both individuals and public health more broadly. Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes. Body fat...

The Effect of Body Fat Distribution

Although the influence of obesity on pulmonary function tests has been examined, the role of body fat distribution has received limited attention. Pulmonary studies of patients severely affected by upper body obesity suggest they have more severely compromised lung volumes than obese patients with lower body obesity. We examined 42 healthy but normal or mildly obese men to determine if body fat...

Body fat, body fat distribution and the respiratory system: a "fat neck" syndrome?

Sex differences in measures of body fat and body fat distribution in the elderly.

This study describes sex differences in obesity and body fat distribution using commonly used assessment methods in 140 men and 245 women age 65-96 years from Rancho Bernardo, California. Significant correlations were shown among all obesity measures. The waist/hip ratio was more strongly correlated with the truncal fat/leg fat ratio in women than in men. The waist/hip ratio correlated signific...

Obesity, body fat distribution and breast cancer.

Abstract Strong epidemiological data exists implicating anthropometric risk factors in breast cancer aetiology. In premenopausal women the risk of breast cancer increases with increased height, yet decreases with increasing weight and BMI. Although the evidence is not strong, a counter-intuitive positive relationship between central adiposity and premenopausal breast cancer risk is emerging. In...